专利名称：MODIFIED MICROORGANISMS FOR
CHEMICAL PRODUCTION
发明人：Xuan Wang,Reed Cartwright,Christian
Sievert,Taylor Loeffler,Lizbeth Nieves,LarryPanyon,Chandler Morris
申请号：US15176866申请日：20160608
公开号：US20160362456A1公开日：20161215
摘要：The present invention relates to increasing xylose utilization in industrialmicrobe by inducing mutations in the regulator genes, crp and xylR. Thus the invention isdirected to isolated nucleic acid sequences that encode mutations in the crp gene andthe xylR gene and recombinant bacterium that express mutated CRP and XylR. In someembodiments, the mutation results in a point mutation at residue 142 of the CRP proteinand/or at point mutation at residues 121, 182 and/or 363 of the XylR protein (based onthe protein sequences in ). The invention also includes methods of using the recombinantbacterium.
申请人：Arizona Board of Regents on behalf of Arizona State University
地址：Scottsdale AZ US
国籍：US
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