专利名称：NEURODEGENERATIVE DISORDERS发明人：GREENFIELD, Susan申请号：AU2018260893申请日：20181108公开号：AU2018260893B2公开日：20200507
摘要：#$%^&*AU2018260893B220200507.pdf##### 70166PCT1 - 55 Abstract A cyclicpolypeptide, derivative or analogue thereof, comprising an amino acid sequence derivedfrom the C-terminus of acetylcholinesterase (AChE), or a truncation thereof. 5 [Figure: 11]8/16 Figure 11 A DAEFR HDSGY EVHHQ KLVFF AEDVG SNKGA IIGLM VGGVV IA T30 KAEFHRWSSY MVHWK NQFD YSKQD RCSDL T14 AEFH RWSSY MVHWK TIS NQFDH YSKQDRCSDL Figure 12 Orthosterio site Alosteric site MLA A~h, Chol A 0 PNU12 IVM, GAL, T30Figure 13 160 Calcium influx 140 Lii 120 C2 100- - - - - - -- - - - -- -- - 80 Go -3 -2 -1 0 1 Log[NBP-14]
申请人：Neuro-Bio Limited
代理人：AJ PARK
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